Daily Briefing

4 minute read

Mapped: US flu activity spikes ahead of the holidays


Flu rates are rapidly rising across the United States, with hospitalizations hitting their third-highest level in 15 years according to CDC data. Here's what experts recommend you do to stay safe this holiday season.

Where the flu stands now

According to CDC, positive flu tests for the week ending Dec. 6 were up 8.1% nationwide, and the cumulative flu hospitalization rate was 6.9 per 100,000 population, almost double the rate seen during the same time last flu season. This marks the third-highest rate recorded since 2010, behind the 2022-23 and 2023-24 seasons.

CDC estimates that so far this flu season, there have been at least 2.9 million illnesses, 30,000 hospitalizations, and 1,200 deaths. Additionally, one influenza-associated pediatric death was reported during the week ending Nov. 22, the first of the 2025-2026 season.

While CDC says that overall flu severity indicators remain low, the agency also noted that some indicators are elevated and that flu season is just beginning.

Some states are seeing higher rates of influenza-like illnesses (ILIs) than others, including Colorado, New York, Louisiana, and New Jersey, all of which CDC designated as having "high" ILI levels.

Meanwhile, the World Health Organization (WHO) said that at least 27 of the 38 countries in its European region have reported "high or very high influenza activity," with more than half of patients with flu-like symptoms testing positive in six countries.

So far this flu season, the dominant strain of the flu has been an H3N2 virus, according to CDC. For the week ending Dec. 6, 86% of influenza viruses reported by public health labs were H3N2.

Specifically, a new variant of H3N2, called H3N2 subclade K, has been the dominant flu strain within the United States. WHO said the new variant has accounted for up to 90% of confirmed flu cases in the European region but added there's no evidence the variant is causing more severe diseases.

Early analysis from the U.K. Health Security Agency found that subclade K has seven gene changes on an important segment of the virus. Those mutations change the shape of the region, which makes it harder for the body's immune system to recognize.

Scientists in the Unted Kingdom estimate that subclade K has a reproduction number of 1.4, meaning each infected person spreads the virus to 1.4 others on average. Typically, the seasonal flu has a reproduction number closer to 1.2, which means a higher number could lead to millions of additional cases.

"Flu comes around every winter, but this year is a little different," said Hans Henri Kluge, WHO's regional director for Europe. "It shows how just a small genetic variation in the flu virus can place enormous pressure on our health systems." Kluge added that the flu season is expected to peak in late December or early January. 

How to stay safe this holiday season

According to the Automobile Association of America, more than 122 million Americans will be traveling during the 13-day holiday period this month, including more than 13 million in crowded trains, buses, and airplanes.

With flu rates rising across the country, physician Nina Shapiro offered tips in Forbes on how you can stay safe while traveling this holiday season:

  • Get your flu shot: While this year's flu vaccine may not be as good of a match given the new variant circulating, WHO said early data from the United Kingdom confirmed the vaccine lowered the risk of severe illness from H3N2 and is "especially important for those at higher risk, including older persons, those with underlying conditions, pregnant women and children."
  • Wash your hands with soap and water: After you're done washing your hands, dry them with either a clean towel or mechanical air dryer, Shapiro said, adding that hand sanitizer "holds a very distant second place" compared to washing your hands.
  • Postpone travel if someone's sick: If you or your family members are sick, consider postponing holiday travel plans to avoid spreading viruses, Shapiro said.
  • Use nasal saline: Using any brand and any form of nasal saline regularly during respiratory virus season has been shown to mechanically reduce viral load in the nose, which is where most respiratory pathogens start, Shapiro said. This has been shown to reduce incidence, severity, and duration of many viral infections.
  • Maintain healthy routines: Make sure you're getting enough sleep, exercising, eating healthily, and minimizing your alcohol consumption this holiday season, Shapiro said.

(Shapiro, Forbes, 12/16; Bean, Becker's Clinical Leadership, 12/16; Henley, The Guardian, 12/17; Goldstein/Coleman, New York Times, 12/16)


SPONSORED BY

INTENDED AUDIENCE

AFTER YOU READ THIS

AUTHORS

TOPICS

INDUSTRY SECTORS

RELATED RESOURCES

Don't miss out on the latest Advisory Board insights

Create your free account to access 1 resource, including the latest research and webinars.

Want access without creating an account?

   

You have 1 free members-only resource remaining this month.

1 free members-only resources remaining

1 free members-only resources remaining

You've reached your limit of free insights

Become a member to access all of Advisory Board's resources, events, and experts

Never miss out on the latest innovative health care content tailored to you.

Benefits include:

Unlimited access to research and resources
Member-only access to events and trainings
Expert-led consultation and facilitation
The latest content delivered to your inbox

You've reached your limit of free insights

Become a member to access all of Advisory Board's resources, events, and experts

Never miss out on the latest innovative health care content tailored to you.

Benefits include:

Unlimited access to research and resources
Member-only access to events and trainings
Expert-led consultation and facilitation
The latest content delivered to your inbox

This content is available through your Curated Research partnership with Advisory Board. Click on ‘view this resource’ to read the full piece

Email ask@advisory.com to learn more

Click on ‘Become a Member’ to learn about the benefits of a Full-Access partnership with Advisory Board

Never miss out on the latest innovative health care content tailored to you. 

Benefits Include:

Unlimited access to research and resources
Member-only access to events and trainings
Expert-led consultation and facilitation
The latest content delivered to your inbox

This is for members only. Learn more.

Click on ‘Become a Member’ to learn about the benefits of a Full-Access partnership with Advisory Board

Never miss out on the latest innovative health care content tailored to you. 

Benefits Include:

Unlimited access to research and resources
Member-only access to events and trainings
Expert-led consultation and facilitation
The latest content delivered to your inbox
AB
Thank you! Your updates have been made successfully.
Oh no! There was a problem with your request.
Error in form submission. Please try again.