Implementing a population health strategy within a life sciences organization requires structural change, new capabilities, and deep alignment with provider priorities. AbbVie launched its Population Health team to support health systems, help patients meet optimal treatment targets, and reduce total cost of care. Rather than focusing on branded product messaging, the team prioritizes neutral, data-driven partnerships that help providers optimize care. We sat down with Brendan Dornbusch, general manager of Population Health at AbbVie, to learn how his team navigated internal barriers and positioned AbbVie as a strategic partner to providers.