Oncology biomarker testing (also known as mutation, genomic, or molecular testing) uses laboratory tests, including companion diagnostics, to help the health care teams gather as much information as possible about a patient’s cancer, ideally before treatment begins, and uncover whether the patient has an actionable biomarker. A companion diagnostic (CDx) is typically an in vitro diagnostic that detects a perfective biomarker to determine whether the patient will respond to a specific treatment.
Health systems
Advisory Board’s research has found that oncology biomarker testing aligns with many of a health system’s broader strategic goals. In the future, health systems will increasingly use oncology biomarker testing to deliver personalized care to patients and advance their precision medicine initiatives.
Biomarker testing can also help organizations drive towards value-based care by improving the overall value of care across the entire patient journey—from diagnosis to treatment selection and outcomes.
Additionally, organizations can use biomarker testing to elevate their oncology department. Advisory Board found that best-in-class organizations utilize biomarker testing to help improve outcomes and strengthen the quality of the oncology care they provide.
Providers
Providers can use oncology biomarker testing to help make more informed care and treatment decisions based on a patient’s genetic makeup.
Notably, biomarker testing can help providers get patients on the right treatment, at the right time. In fact, 37.6% of cancer patients in one study of 5954 patients with refractory malignancies had therapeutically actionable genetic alterations, meaning they could be matched to existing drugs, across many different cancer types. Providers can also use biomarker testing to indicate a patient’s increased risk or susceptibility to a given disease, predict the natural history of disease without further intervention, or predict an outcome following an intervention.
Patients
Oncology biomarker testing may help improve patients’ treatment success and outcomes. It also allows patients to avoid trial-and-error and more quickly receive the appropriate treatments for their genetic makeup.
Recommendations from Advisory Board’s research
AstraZeneca focuses on the discovery, development and commercialisation of prescription medicines in Oncology and BioPharmaceuticals, including Cardiovascular, Renal & Metabolism, and Respiratory & Immunology.
This brochure is sponsored by AstraZeneca for educational purposes only. The content, views, and opinions contained within the cheat sheet are copyrighted by Advisory Board and all rights are reserved. Advisory Board experts wrote the content, conducting the underlying research independently and objectively. Advisory Board does not endorse any company, organization, product or brand mentioned herein.
This brochure is sponsored by AstraZeneca. Advisory Board experts wrote the report, conducting the underlying research independently and objectively. AstraZeneca had the opportunity to review the brochure.
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