Advisory Board’s research estimates an approximate $100 billion annual national cost savings opportunity stemming from unwarranted care variation. Recent policy shifts and changes to traditional funding streams are exacerbating pressures on health systems at a time when rising costs and ageing patient populations are already upending health systems’ business and care delivery models. Most organizations have already tapped out traditional cost savings strategies and are now looking for ways to simultaneously reduce costs and enhance operational efficiency without compromising care quality.