Expert Insight

3 minute read

4 ways lab teams use AI to streamline workflows

Staffing shortages aren’t going away. Mayo Clinic Laboratories shows how AI helps labs absorb volume, rebalance workloads, and keep quality high across the workflow.

Like other clinical teams, labs are embracing AI tools to offset workforce instability and shortages. Lab technologist and technician turnover will contribute to approximately 22,600 FTE annual openings over the next few years.1 Hiring for these positions can take three months to a year, leaving understaffed teams to manage the growing workload.2

Innovative labs use AI workflow tools to ease the pressure. These tools don’t change how tests are performed but support the daily work that surrounds them. Learn how teams at Mayo Clinic Laboratories leverage AI tools to improve four points of workflow inefficacy.

1. Automate specimen intake

Specimen intake can cause inefficiency early on as teams work through slides, labels, and requisitions that don’t always align in format or completeness. Entering a case into the system can take longer than expected when staff must interpret and enter that information line by line.

AI now assembles much of that information. In some cases, a single image supplies enough information to populate multiple required fields at once. Work that previously required several steps of manual entry now happens earlier and more consistently. That shift changes how intake fits into the workflow. By the time a technologist steps in, the case already resembles a complete intake, allowing them more time to confirm accuracy and quality.

2. Plan capacity and workflow needs

Lab workload fluctuates unpredictably and is largely dependent on the schedules of the clinical teams the labs support. Labs often struggle to coordinate schedules with upstream clinical teams and are left adjusting their staffing levels in real time.

Teams at Mayo use AI to identify volume patterns and plan their schedules accordingly. AI pulls in information the lab already has, including procedures currently scheduled, how similar days have historically played out, and uses that to signal where demand is likely to spike. Instead of waiting for backup to appear, supervisors can redistribute work or adjust the order in which cases move through the lab. In some settings, the same approach extends to forecasting supplies, such as estimating how much blood will be needed for a given set of procedures.

3. Support early analysis

Preparing a case for analysis and interpretation involves a heavy amount of manual work. Staff usually clean large volumes of data, reshape how it’s displayed, and narrow in on the parts that matter.

AI helps organize the incoming data into a clearer view, pinpoints areas that may need attention, and establishes an initial frame for review. In practice, this means work involving repetitive fine-tuning now looks more like a quick confirmation step. The reviewer is still responsible for quality maintenance, but they are reviewing data against a prepared starting point rather than building one themselves.

4. Standardize how results are drafted and communicated

Even after a case is fully reviewed, the final step takes time: Turning findings into a report that other clinicians can use. Pathologists must gather details from different tests and reassemble them into a familiar structure, repeating much of the same work from case to case.

AI provides the pathologist with a draft integrating all the relevant inputs. From there, the pathologist reviews, edits, and finalizes the interpretation. In digital pathology workflows, this can also include automatically tallying elements like positive and negative cells across large images and feeding those counts into the report. The result is less time spent constructing the write-up and more consistency in how results are presented.

Parting thoughts

Across Mayo Clinic Laboratories, staff are focused on using AI to strengthen the parts of the workflow that most directly support day-to-day operations, from front-end intake and workload balancing to reporting and interpretation. These enhancements don’t change the test itself, but they help staff streamline processes, improve consistency, and make it easier for teams to maintain performance as volume grows.

Read Mayo Clinic Laboratories’ full piece on how teams use AI across the workflow, from intake through interpretation.

1 Occupational Outlook Handbook: Clinical Laboratory Technologists and Technicians. U.S. Bureau of Labor Statistics. August 28, 2025.

2 Garcia E, et al. The American Society for Clinical Pathology 2024 Vacancy Survey of Medical Laboratories in the United States. American Journal of Clinical Pathology. September 29, 2025.


About the sponsor

Mayo Clinic Laboratories provides specialized laboratory testing for serious and complex conditions to advance patient care worldwide. For 55 years, Mayo Clinic Laboratories has helped physicians answer the toughest clinical questions with confidence and empowered hospitals to elevate care within their communities. Through an integrated diagnostics ecosystem powered by Mayo Clinic, the organization offers access to 4,300 tests and pathology services, delivering trusted, timely answers to clinicians and patients. Learn more here.

This article is sponsored by Mayo Clinic Laboratories, an Advisory Board member organization. Representatives of Mayo Clinic Laboratories helped select the topics and issues addressed. Advisory Board experts wrote the report, maintained final editorial approval, and conducted the underlying research independently and objectively. Advisory Board does not endorse any company, organization, product or brand mentioned herein.

To learn more, view our editorial guidelines.


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This article is sponsored by Mayo Clinic Laboratories. Advisory Board experts wrote the article, maintained final editorial approval, and conducted the underlying research independently and objectively.

Learn more about Mayo Clinic Laboratories


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AFTER YOU READ THIS
  • You will understand how AI automates specimen intake to cut manual entry and errors.
  • You will learn how labs use AI to forecast demand and rebalance staffing proactively.
  • You will understand how AI supports analysis and standardizes lab reports for consistency.

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Emily Schmidt

Senior writer and editor, Sponsorship

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