Before the Covid-19 epidemic, care variation reduction (CVR) was a mainstay on the C-suite agenda for its potential to drive cost savings and improve care quality at the same time. Now, both mandates are even more acute. Clinical executives are under tremendous pressure to find clinical cost savings, while working with a public and a clinical workforce that is increasingly sensitive to clinical safety and quality. In response, hospitals and health systems are recommitting to their CVR strategy.