Methodology

To create the list, Fortune partnered with Statista to evaluate companies on three dimensions of innovation:

• Product innovation, which includes the introduction of new products or services and regular improvement of existing products and services
• Process innovation, which refers to the development and use of new and innovative technologies/production processes, as well as innovative use of digitalization
• Innovation culture, which measures the extent that a company fosters a spirit of entrepreneurship and creativity among its employees

Each dimension accounted for a third of a company's score, which ranged from 0 to 100. To determine each company's score, Statista conducted several surveys to collect both internal and external views on a company's innovation. Roughly 34,000 employees and over 3,000 experts participated in surveys for the list.

Statista also evaluated the strength of a company's patent portfolio based on the Patent Asset Index, which considers technology relevance and market coverage to determine competitive impact. Patent data was provided by LexisNexis Intellectual Property Solutions.

A total of 300 companies from 17 industries and 36 U.S. states were included on the list. The industries with the most innovative companies were technology, financials, and healthcare. 

The most innovative companies in healthcare

In total, 53 healthcare companies — including 22 Advisory Board members — made the list, including health systems, insurers, pharmaceutical companies and more:

4. Abbott Laboratories

20. Zimmer Biomet Holdings*

21. Bristol-Myers Squibb

28. Johnson & Johnson*

31. Merck

34. Pfizer*

44. Boston Scientific*

45. Stratus Medical

47. Amgen

54. AbbVie*

64. Houston Methodist*

70. Carna

72. Cleveland Clinic*

75. Cincinnati Children’s Hospital Medical Center

81. Aion Biosystems

87. Stryker

89. Eli Lilly*

90. Cigna Group

98. Humana

114. Cedars-Sinai Health System*

119. Quest Diagnostics*

122. Abridge AI

123. Cardinal Health

124. Piedmont Healthcare*

126. 4D Molecular Therapeutics

137. Thermo Fisher Scientific

143. Mass General Brigham

146. UnitedHealth Group**

151. Labcorp Holdings*

155. Elevance Health

171. Boston Children's Hospital

182. Akron Children's Hospital

195. Northwell Health

213. McKesson*

226. Ann & Robert H. Lurie Children's Hospital of Chicago

230. DaVita

231. Johns Hopkins Medicine*

239. ADMA Biologics

242. Select Medical Holdings

246. CommonSpirit Health

251. Mount Sinai Health System*

253. Highmark Health*

257. Sutter Health*

263. Intermountain Healthcare*

264. UMass Memorial Health Care*

272. Regeneron Pharmaceuticals

273. Kaiser Permanente*

277. Baylor Scott & White Health*

284. AdhereHealth

292. Prisma Health

294. Sanford Health

295. HealthPartners*

300. Moderna

*Denotes an Advisory Board member

**Advisory Board is a subsidiary of Optum, a division of UnitedHealth Group. All Advisory Board research, expert perspectives, and recommendations remain independent.  

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• Topic: Clinical innovation