Library

| Daily Briefing

Your blood type may determine your blood clot risk


Blood type: It can predict your stroke risk, personality type, post-op mortality risk, and now your risk of blood clots.

Copenhagen University Hospital researchers have found that individuals with AB blood type are 4% more likely to develop blood clots that individuals with O blood type.

Blood clots that form in the lower extremities—called deep-vein thrombosis (DVT)—can become deadly if they break off and become lodged in pulmonary arteries and cause embolisms. Each year, about two million people suffer from DVT, and as many as 200,000 die as a result of complications.

For the study, Borge Nordestgaard and colleagues analyzed blood type and genetic clotting-disorder information on 66,001 individuals who participated in two Danish studies between 1977 and 2010. Specifically, they examined patients with mutations in Factor V Leiden genes and in a clotting agent called prothrombin.

They found that:

  • Patients with AB blood type had a 4% higher risk of venous-blood clotting compared with participants with O type blood;
  • Patients with a Factor V—a genetic mutation—were seven times more likely to suffer from a blood clot than those without any variants of the mutation; and
  • Patients with a clot-favoring prothrombin mutation had an 11-fold increased risk of developing blood clots.

The researchers also found that people with A, B, and AB type blood retain up to 30% higher levels of the von Willebrand clotting factor in the blood compared with O-type people.

Overall, researchers estimated that having an AB blood type contributes to about 20% of the risk for blood clots. By comparison, being overweight accounts for 16%; Factor V accounts for 10%; smoking accounts for 6%; and prothrombin accounts for 1%, respectively (Sifferlin, TIME, 2/4).


SPONSORED BY

INTENDED AUDIENCE

AFTER YOU READ THIS

AUTHORS

TOPICS

Don't miss out on the latest Advisory Board insights

Create your free account to access 2 resources each month, including the latest research and webinars.

Want access without creating an account?

   

You have 2 free members-only resources remaining this month remaining this month.

1 free members-only resources remaining this month

1 free members-only resources remaining this month

You've reached your limit of free monthly insights

Become a member to access all of Advisory Board's resources, events, and experts

Never miss out on the latest innovative health care content tailored to you.

Benefits include:

Unlimited access to research and resources
Member-only access to events and trainings
Expert-led consultation and facilitation
The latest content delivered to your inbox

You've reached your limit of free monthly insights

Become a member to access all of Advisory Board's resources, events, and experts

Never miss out on the latest innovative health care content tailored to you.

Benefits include:

Unlimited access to research and resources
Member-only access to events and trainings
Expert-led consultation and facilitation
The latest content delivered to your inbox
AB
Thank you! Your updates have been made successfully.
Oh no! There was a problem with your request.
Error in form submission. Please try again.