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Continue LogoutHospital-acquired conditions (HACs) like pneumonia are difficult to detect and costly to treat. It’s common for data-driven organizations to address this challenge by using data to identify patients at risk of deterioration and then to implement a standard treatment plan. This retroactive approach is starving systems of valuable resources because it targets patients at risk of deterioration instead of preventing deterioration in the first place.
Flagler Hospital is a private not-for-profit community hospital in St. Augustine, Florida. The 335-bed acute care center has 400 physicians on staff.
Flagler took a unique approach, using artificial intelligence (AI) to proactively identify care paths that prevent HACs. Partnering with Symphony AyasdiAI, a machine intelligence software company, helped Flagler take advantage of the readily available data that sits in electronic health records (EHRs). Together, Flagler and Symphony AyasdiAI implemented a data-driven solution using AI to identify the best care paths, develop new order sets, and reduce care variation. Flagler started with pneumonia and has since moved on to cover 11 other conditions.
Flagler advanced beyond the pneumonia pilot stage to successfully implement standardized pneumonia order sets. Within the first few months of implementation, length of stay (LOS), mortality, and costs decreased.
Instead of using AI to detect patients with HACs, Flagler used AI to proactively generate care paths that protect patients from developing these conditions. Flagler’s IT and physician teams then worked together to match the care paths to a standardized order set. A successful pneumonia pilot showed improved care outcomes and decreased costs, encouraging Flagler to permanently implement standardized order sets for pneumonia.
After piloting the AI application, Flagler identified four elements that helped them successfully implement AI-generated standardized order sets:
In any cross-functional project, it’s important to get executive support from the beginning to enable collaboration and manage expectations. Without the support of executives, it’s difficult to weather unexpected results or lengthened timelines. The project could be doomed to fail before it even begins.
It can be especially hard to establish executive support and get AI projects off the ground because there are few AI project precedents to help determine expected results and predict ROI.
Flagler’s advice is to resist the temptation to offer too many guarantees. Instead, understand your limits and make a contingency plan. You can use the project as an opportunity to learn—from success and failure. Here are Flagler’s tips to pitch an AI project.
Working with an AI vendor is an investment of both time and money. Even the best products aren’t plug-and-play solutions because every organization is different and will require different levels of support throughout the project. When choosing a vendor, Flagler looked for a true partner to work alongside and one that would help yield the greatest value for both organizations.
Symphony AyasdiAI’s experience in working with other health systems helped them recognize how Flagler’s workflows were different from other systems and where those differences created problems in the code. Where it would have taken weeks for Flagler’s team to solve a simple problem in the code, Symphony AyasdiAI provided an immediate solution by adjusting the code as needed. Relying on Symphony AyasdiAI as a partner helped save time and effort as Flagler prepared to launch the pilot.
Flagler’s team added value to the partnership by confirming clinical results. Symphony AyasdiAI’s solution uses unsupervised learning to recognize patterns in large amounts of data. This is different from supervised learning models where researchers train the algorithm by feeding it specific variables. Although bias is less of a concern in unsupervised models than in supervised models because the algorithm isn’t trained by researchers, there’s still a “black box” problem. Black box problems refer to our inability to understand how the AI makes decisions to create patterns. This is why it was important for Flagler to validate suggested patterns in the data. For example, the solution showed that early use of antibiotics and steroids were effective treatments for pneumonia patients. Even though Flagler’s team couldn’t say how the AI solution made that connection, they could confirm that clinical research supports the early use of these substances to reduce LOS and adverse outcomes.
EHRs are full of valuable data. Flagler realized that with very little work, AI could produce actionable insights from their data. Dr. Michael Sanders, CMIO of Flagler Hospital, thinks of EHRs as the new textbook of medicine—there’s a lot to learn if you can just pull out the right information.

Flagler’s eight-person informatics team wrote 2,500 lines of Structured Query Language (SQL) code to pull the data for the pneumonia pilot from the EHR. Fortunately, the data requirements were well defined and already standard outputs of the EHR, so it was relatively quick and simple to get the data.
Because the AI solution could comb through different kinds of data, Flagler’s team also pulled data from sources outside of the EHR. The other two sources of data were the financial system and the surgical system. The informatics team collected and recorded data for everything that happened to patients from admission to discharge, including standard lab results and vital signs. The team even recorded small details like what meals the patients ate and the exact times they ate each day.
At this point, the solution recognized patterns in Flagler’s data and sorted the patients into treatment groups. Each group represented a typical patient population with similar treatment patterns. The software analyzed the data to create a care path for each group and displayed a dashboard comparing each group by costs, mortality, and care outcomes.
Flagler’s team used the dashboard to identify the optimal treatment group (the group with the best outcomes at the lowest cost) and used the generated care path as a template for a new order set.


The hardest part of the project at Flagler was matching the AI-generated care path to a standard order set. It wasn’t a data or technical problem—the challenge was convincing physicians to change their workflows. Flagler overcame initial hesitation by helping physicians learn from each other, both as project champions and by sharing data comparisons with peers.
Flagler encourages physician adoption and collaboration in all data-driven projects with the help of their Physician IT (PIT) crew. The PIT crew consists of physicians from every department who act as project champions. Whenever IT projects affect workflows, the PIT crew decides if the workflow changes are reasonable, how the change should be implemented, and what the drawbacks are. The PIT crew is then responsible for helping their peers understand the value of a given project.

Knowing that evidence of success is another essential component for physician adoption, Flagler shared patient outcomes and physician adherence to order sets with physicians. The data was especially meaningful to physicians because they could compare themselves to peers, so they could learn from each other. For many physicians, this was the first time they had access to measurable data-driven results.
With physician support, Flagler successfully reduced five conflicting and duplicative orders sets down to one order set.


During a two-week pilot, the AI solution helped Flagler determine the best order set for pneumonia. Within nine months of implementation, Flagler decreased LOS, rate of admission, and mortality rate, and saved $1.06 million.
1.5 Days reduction in LOS
0.8% Rate of admission, down from 8%
0% Mortality rate, down from 4%
$1.06M Saved
The same solution is currently being applied to 11 other conditions including sepsis, chronic obstructive pulmonary disease (COPD), coronary artery bypass grafting (CABG), and hip and knee replacements. Flagler credits the AI solution for saving 54 lives during the first year of operation.
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