Narrowing the spectrum of antimicrobial utilization

Helen DeVos Children's Hospital | 212-bed children's hospital

Tangible Impact


Annual antimicrobial cost savings attributable to a transition toward more narrow-spectrum, lower cost drugs


HA C. difficile infections avoided in 2013 after establishing an ASP targeted at reducing broad spectrum Abx usage


2013 cost avoidance attributable to a lowering HA C. difficile rates house-wide at HDVCH

Hematology/Oncology patients treated at Helen DeVos Children’s Hospital (HDVCH), a 212-bed children’s hospital in Grand Rapids, Mich., are often treated with multiple antimicrobials. Staff became concerned about the level and breadth of Abx usage in Hem/Onc and the related 23.7 hospital acquired C. difficile rate.

The hospital created a targeted antimicrobial stewardship program (ASP) efforts within the Hem/Onc unit by running unit-specific antibiogram through Quality Compass.

The clinical RPh and pediatric infectious disease physicians rounded together on Hem/Onc to make collaborative Abx decisions. Hem/Onc pilot’s success led to house-wide expansion at HDVCH.

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The transition resulted in significant cost savings and lower infection rates including:

  • Decreased overall Abx usage by 47% between 2012 and 2013
  • Saved $449K in Abx costs and infection in 2013
  • Lowered HA C. difficile rates by 69% in Hem/Onc and 51% house-wide in 2013
  • Received internal funding to expand ASP initiative to Spectrum Health adult hospitals.

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